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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VWF
All Species:
11.52
Human Site:
T2292
Identified Species:
50.67
UniProt:
P04275
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04275
NP_000543.2
2813
309263
T2292
S
G
R
K
V
N
C
T
T
Q
P
C
P
T
A
Chimpanzee
Pan troglodytes
XP_001160508
2813
309213
T2292
S
G
R
K
V
N
C
T
T
Q
P
C
P
T
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540775
3626
389201
H2858
G
N
G
V
I
T
V
H
P
R
S
C
P
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIZ8
2813
309250
T2292
S
G
R
K
I
N
C
T
A
Q
P
C
P
T
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2PC93
5255
560538
A4465
Q
H
P
E
L
C
P
A
Q
S
H
C
L
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665356
2857
313308
T2339
D
Q
Q
R
I
N
C
T
A
L
P
C
T
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
N.A.
24.8
N.A.
83.1
N.A.
N.A.
N.A.
20
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
N.A.
37.8
N.A.
90.8
N.A.
N.A.
N.A.
29.9
N.A.
61.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
13.3
N.A.
86.6
N.A.
N.A.
N.A.
6.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
26.6
N.A.
93.3
N.A.
N.A.
N.A.
20
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
17
34
0
0
0
0
0
67
% A
% Cys:
0
0
0
0
0
17
67
0
0
0
0
100
0
0
0
% C
% Asp:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
50
17
0
0
0
0
0
0
0
0
0
0
0
17
% G
% His:
0
17
0
0
0
0
0
17
0
0
17
0
0
0
0
% H
% Ile:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
17
0
0
0
0
17
0
0
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
67
0
0
0
0
0
0
0
17
0
% N
% Pro:
0
0
17
0
0
0
17
0
17
0
67
0
67
17
0
% P
% Gln:
17
17
17
0
0
0
0
0
17
50
0
0
0
17
0
% Q
% Arg:
0
0
50
17
0
0
0
0
0
17
0
0
0
0
0
% R
% Ser:
50
0
0
0
0
0
0
0
0
17
17
0
0
0
0
% S
% Thr:
0
0
0
0
0
17
0
67
34
0
0
0
17
50
17
% T
% Val:
0
0
0
17
34
0
17
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _